Solvent-free rice husk mediated efficient approach for synthesis of novel imidazoles and their In vitro bio evaluation

An efficient and facile method for the synthesis of substituted imidazoles (10a-10g) has been reported by reacting aldehydes (1–7), benzil (8) ammonium acetate [9] in presence reuseable solid acid catalyst viz. Rice Husk Ash.SO3H (RHA.SO3H) at room temperature. The homogeneity compounds was confirmed melting point thin layer chromatography. All synthesized were characterized 1H NMR FTIR spectral techniques. prepared SEM, TEM X-ray diffraction methods. further tested vitro herbicidal activity against Raphanus sativus L. seeds. also screened their antifungal Rhizoctonia solani Aspergillus niger poisoned food technique method. From bio evaluation data, it found that 10c 10a most active Compound 10g R. fungus highest concentration. 10f shown maximum percentage growth inhibition i.e. 71.89 A. 200 ​μg/mL